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This book contains the art and science in current standards of surgical treatment of pancreatic ductal adenocarcinoma. It explains the clinical role of surgical resection during multimodal treatment in patients with pancreatic ductal adenocarcinoma, novel surgical techniques including extended pancreatectomy and minimally invasive surgery, risk of cancer in IPMN, and the clinical importance of liquid biopsy.

unresectable pancreatic ductal adenocarcinoma --- conversion surgery --- early recurrence --- pancreatic neoplasm/analysis --- pancreatic neoplasm/surgery --- tumor location --- survival --- clinical staging --- branch duct intraductal papillary mucinous neoplasm --- risk factor --- malignancy --- meta-analysis --- laparoscopic --- pancreaticoduodenectomy --- pancreatic cancer --- borderline resectable --- neoadjuvant treatment --- chemoradiotherapy --- prognostic nutritional index --- isolated local recurrence --- pancreatectomy --- pancreatic remnant --- recurrence --- redo surgery --- pancreatic exocrine insufficiency --- adjuvant chemotherapy --- biliary drainage --- prehabilitation --- ERAS --- arterial resection --- total pancreatectomy --- neoadjuvant therapy --- pancreatic ductal adenocarcinoma --- surgical treatment --- technical advances --- pancreatic main duct dilatation --- intraductal papillary mucinous neoplasm --- high grade dysplasia --- invasive carcinoma --- pancreatic cystic neoplasm --- cell-free DNA --- mesopancreas --- superior mesenteric artery --- nerve and fibrous tissues --- lymph node dissection --- R0 resection --- n/a

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The prevalence of diabetes is on the increase in the UK and worldwide, partly due to changes in lifestyle which predispose individuals to overweight and obesity. It is estimated that about 90% of the currently diagnosed adults have type 2 diabetes, and based on the World Health Organisation (WHO) report, about 422 million adults were living with diabetes in 2014 compared with 108 million in 1980; this condition caused about 1.5 million deaths in 2012. In the United States of America, it is estimated that about 30.3 million adults are living with diabetes, with a further 1.5 million new diabetes cases diagnosed every year, representing an increasing prevalence of this condition. Diabetes represents a major public health challenge, despite advances in technology and the pharmaceutical industry. These problems may be in the form of acute or long-term complications. Therefore, in order to attenuate the problems of diabetes, management strategies usually include lifestyle changes such as increased physical activity and dietary interventions. Studies which evaluate the role of nutrition in the management of type 2 diabetes often involve human and animal models as these approaches enable us to have a broader and more in-depth understanding of the condition. In some cases, diabetes may co-exist with other conditions, such as stroke, and these may present unique challenges with regard to nutritional interventions. This Special Issue aims to evaluate the risk factors associated with type 2 diabetes and the role of the diet in the management of people with this condition. This evidence is drawn from both human and animal studies.

low-carbohydrate --- lipids --- carbohydrate restricted diet --- aldosterone --- high fat diet --- interleukin-6 --- rosemary extract --- Hedychium coronarium --- isomaltulose --- low carbohydrate diet --- folk medicine --- free fatty acids (FFA) --- high-density lipoprotein cholesterol --- mushroom --- protein and fat counting --- incretins --- fish oil --- almond --- Japanese --- vitamin D deficiency --- low energy diet --- AMPK --- women --- glycaemic index --- T2DM --- zinc status --- ginseng --- longitudinal analysis --- dietary management approaches --- glucose monitoring --- gut microbiome --- nutritional supplement --- carbohydrate counting --- gestational diabetes --- type 2 diabetes mellitus --- very-low-calorie --- inflammatory parameters --- vitamin D --- subjective appetite --- randomised controlled trial --- total body lean --- insulin secretion --- systematic review --- lactic acid bacteria --- food --- type 2 diabetes --- fish --- zinc intake --- glycaemic control --- diabetes --- dairy products --- glycated haemoglobin --- short chain fatty acids --- glycated hemoglobin A --- glycemic control --- vegetable oil --- standard formula --- cardiovascular risk factors --- DASH --- insulin dosage --- appendicular fat --- body composition --- total body fat --- micronutrients --- 25-OH-D --- obesity --- diabetes reversal --- enteral nutrition --- PUFA --- body mass index --- metabolic syndrome --- lifestyle management --- nutrition --- streptozotocin --- nuts --- enteral tube feeding --- lipid profile --- macronutrients --- triglyceride --- tempeh --- cohort study --- diabetes specific formula --- polyunsaturated fatty acids --- diabetes mellitus --- calcium intake --- hyperglycemia --- epidemiology --- trace elements --- dietary intake --- muscle --- appendicular lean --- peanut --- insulin resistance --- sucromalt --- pancreatectomy --- energy restricted diet --- glycemic index --- type 1 diabetes --- fasting blood glucose --- bariatric surgery --- prediabetes --- aronia --- meta-analysis --- chronic conditions --- diabetes management --- dietary pattern --- diet quality --- lipid parameters --- feces